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If you’re looking for the perfect workout that blends calorie-burning cardio, total-body strength training, and functional conditioning—all in just 45 minutes—this full body cardio and strength workout is exactly what you need. Designed to challenge your muscles, elevate your heart rate, and improve overall fitness, this routine is ideal for women who want an efficient, balanced, and empowering workout they can do at home or in the gym. This 45-minute full body cardio and strength workout combines compound lifts, metabolic movements, and interval-based cardio sections to create a highly effective training session that boosts strength, burns fat fast, and improves conditioning—all while building lean muscle and enhancing endurance. Whether your goal is weight loss, muscle toning, or improving your overall fitness, this routine delivers everything you need in one powerful session.
A 45-minute hybrid session is the sweet spot for women who want maximum results in minimum time. This specific structure delivers multiple benefits:
Mixing strength and cardio creates a metabolic effect that increases calorie burn not only during the workout but for hours after. This elevated post-exercise burn is known as EPOC (Excess Post-Exercise Oxygen Consumption).
Using compound strength exercises—like squats, deadlifts, rows, and presses—activates multiple muscle groups at once, building functional strength and sculpting lean muscle.
The cardio intervals throughout the workout boost heart health, lung capacity, stamina, and athletic performance.
A full-body split allows you to hit all major muscle groups in one session, improving balance, stability, and total-body strength—perfect for women with busy schedules.
Even though it’s a challenging 45-minute session, the format is easy to follow and appropriate for all levels, with modifications for beginners and progressions for advanced lifters.
This session is divided into four strategic phases:
Each phase is designed to maximize performance, protect your joints, elevate your heart rate safely, and deliver the best results possible.
Your warm-up should gradually elevate your heart rate, increase blood flow to muscles, and activate your core and glutes.
Perform each exercise for 30–45 seconds.
These moves warm up the major muscle groups you’ll use during the workout, prepare mobility, and activate stabilizers to help prevent injury.
This strength circuit uses compound lifts to activate your legs, core, glutes, back, shoulders, and arms. Complete the circuit 3 rounds, resting 60–90 seconds between rounds.
A powerful move that targets your quads, glutes, shoulders, and core.
How to do it:
Hold dumbbells at shoulder height, squat deeply, then press them overhead as you stand.
Benefits: Total-body power and metabolic burn.
Strengthens your back, biceps, and core stability.
How to do it:
Hinge at the hips, keep your spine neutral, and pull the weights toward your ribcage.
Benefits: Improves posture, defines back muscles, and balances out pressing work.
Targets glutes, quads, and hamstrings while improving balance.
How to do it:
Step back into a lunge, drop the back knee, drive through the front heel.
Benefits: Stabilizing strength for hips, legs, and glutes.
Classic upper-body and core strengthening movement.
How to do it:
Stay in a straight plank, lower your chest, push back up.
Modifications: Knees down, incline push-up, elevated hands.
Benefits: Tones chest, shoulders, triceps, and core.
Key for developing posterior chain strength.
How to do it:
Hinge at your hips, lower weights to mid-shin, keep your back straight.
Benefits: Builds strong hamstrings, glutes, and lower back stability.
Targets chest, triceps, and shoulders.
How to do it:
Press weights from chest level to full extension.
Benefits: Upper body strength and definition.
Engages your core and improves anti-rotation stability.
How to do it:
Tap opposite shoulder while minimizing hip movement.
Benefits: Strengthens core, shoulders, and improves balance.
After strength training, your muscles are fatigued but primed for fast, intense cardio work. This portion boosts your heart rate, burns calories fast, and improves conditioning.
Perform each movement for 45 seconds, rest 15 seconds, repeat the whole circuit 3 rounds.
Explosive cardio move that spikes your heart rate.
Lift your knees quickly and pump your arms.
Full-body power movement.
Modification: Fast bodyweight squats.
Targets core, legs, and shoulders while delivering cardio conditioning.
Modify by slowing the pace.
Great for coordination, speed, and leg power.
Ultimate full-body cardio exercise.
Modify by stepping back instead of jumping.
Core-stability plus heart-pumping movement.
Modify by stepping feet out.
Sprint your feet and “drop” into a squat every few seconds.
Fantastic metabolic finisher.
This 15-minute conditioning block maximizes calorie burn and challenges endurance.
Never skip the cool-down; it helps reduce soreness and improve mobility.
Hold each stretch for 20–30 seconds.
This helps lower your heart rate and improves recovery.
The combination of strength and cardio maximizes total energy expenditure.
You’ll sculpt arms, legs, core, and glutes while gaining strength.
Everyday tasks feel easier as you build strength, mobility, and stability.
Cardio intervals push your lungs and heart to get stronger.
Exercise releases endorphins while balancing hormones like cortisol.
Strength training boosts metabolism long-term by increasing lean mass.
Requires minimal equipment and adapts to any fitness level.
Whether you’re a beginner or advanced, set a pace that feels challenging yet maintainable.
Choose a weight that feels difficult by the last 2 reps but doesn’t break your form.
Proper mechanics prevent injury and ensure you’re activating the right muscles.
A strong core enhances balance and power.
Increase weights
Increase reps
Shorten rest periods
Add more explosive variations
3–4 sessions per week will produce visible results in strength, endurance, and tone.
This full-body cardio and strength workout is ideal for:
This routine fits seamlessly into weight loss goals, toning goals, strength-building phases, or overall general fitness improvement.
Here is how you can include this workout in a weekly training schedule:
Monday: 45-Minute Full Body Cardio + Strength Workout
Tuesday: 20–30 Minute Pilates or Mobility Flow
Wednesday: Upper Body Strength Day
Thursday: 45-Minute Full Body Cardio + Strength Workout
Friday: Lower Body Strength Day
Saturday: Optional Light Cardio or Yoga
Sunday: Rest / Recovery
This structure allows you to build muscle, maintain balance, and avoid overtraining.
Fueling your body properly before and after workouts enhances performance and recovery.
Aim for at least 70–100 oz of water daily, especially during strength and cardio training.
This 45-minute full body cardio and strength workout is one of the most effective ways for women to burn calories, increase strength, tone their muscles, and improve cardiovascular endurance—all in a single empowering session. With a balance of strength training, cardio intervals, functional movement patterns, and core work, this routine delivers full-body benefits that support long-term fitness and health.
Whether you’re a beginner or advanced lifter, this workout provides structure, challenge, and results. Add it to your weekly routine to boost metabolism, sculpt lean muscle, and feel stronger, fitter, and more confident.
To get even more out of your 45-minute full body cardio and strength workout, you can mix it into a larger routine using other Women’s Fit Club resources. On days when you’re short on time, try the 30-Minute Strength and Cardio Workout for Full-Body Fat Burn for a faster but still intense combo of lifting and conditioning from home or the gym. If you want to upgrade your heart-pumping intervals, explore the Top Fat-Burning Cardio Exercises guide to plug new movements into your cardio blocks and keep results coming. For a deeper focus on lifting technique and progression, pair this routine with The Best Full Body Strength Workout for Women to build a strong foundation and improve your form on key compound moves. On active recovery or lighter training days, rotate in ideas from 15 Full Body Cardio Workouts You Can Do Anywhere so you stay consistent.
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